Brand Name: Gris-PEG

Generic Name: Griseofulvin (GRIS-ee-oh-FUL-vin)

What is Gris-PEG (griseofulvin)?

Griseofulvin is used to treat fungal infections of the skin, hair, and nails such as jock itch, athlete's foot, and barber's itch.

Griseofulvin is an antifungal medication. It is like an antibiotic but is used to treat fungal infections.

Griseofulvin may also be used for purposes other than those listed in this medication guide.

Gris-PEG Ultramicrosize Tablets are used for:

Gris-PEG Ultramicrosize Tablets are an antifungal agent. It works by making the skin more resistant to fungal growth.

Treating ringworm infections of the skin, hair, and nails. It is also used to treat athlete's foot and "barber's itch." It may also be used for other conditions as determined by your doctor.

Do NOT use Gris-PEG Tablets if:

you are pregnant

you have liver failure or a blood disease (eg, porphyria)

you are allergic to any ingredient in Gris-PEG Ultramicrosize Tablets

Contact your doctor or health care provider right away if any of these apply to you.

How Taken

Accurate diagnosis of the infecting organism is essential. Adults: Daily administration of 330 mg (as a single dose or in divided amounts) will give a satisfactory response. Children: Approximately 3.3 mg per pound of body weight per day is an effective dose for most children.

Warnings/Precautions

Because Gris-PEG can make you sensitive to light, avoid exposure to intense natural or artificial sunlight. Notify your doctor if you develop lupus erythematosus (a form of rheumatism) or a lupus-like condition. Signs and symptoms of lupus include arthritis, red butterfly rash over the nose and cheeks, tiredness, weakness, sensitivity to sunlight, and skin eruptions. If you are being treated with Gris-PEG for an extended period of time, your doctor should perform regular tests, including periodic monitoring of kidney function, liver function, and blood cell production. Gris-PEG has not been proved safe and effective for the prevention of fungal infections. Gris-PEG may decrease the effectiveness of birth-control pills. Use additional protection while you are taking Gris-PEG. Men should wait at least 6 months after finishing therapy with Gris-PEG before they father a child. Women should avoid becoming pregnant while they are taking the drug.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once.

Possible Side Effects

When adverse reactions occur, they are most commonly of the hypersensitivity type such as skin rashes, urticaria, erythema multiform-like drug reactions, and rarely, angioneurotic edema, and may necessitate withdrawal of therapy and appropriate countermeasures. Paresthesias of the hands and feet have been reported rarely after extended therapy. Other side effects reported occasionally are oral thrush, nausea, vomiting, epigastria distress, diarrhea, headache, fatigue, dizziness, insomnia, mental confusion, and impairment of performance of routine activities. Administration of the drug should be discontinued if granulocytopenia occur. When rare, serious reactions occur with Gris-PEG, they are usually associated with high dosages, long periods of therapy, or both.

Storage

Store Gris-PEG tablets at controlled room temperature 15°-30°C (59°-86°F) in tight, light-resistant containers.

Overdose

Any medication taken in excess can have dangerous consequences. If you suspect an overdose of Gris-PEG, seek emergency medical treatment immediately.

More Information

Gris-PEG may intensify the effects of alcohol. If you drink alcohol while taking this medication, your heart may start beating faster and your skin may be flushed. If Gris-PEG is taken with certain other drugs, the effects could be increased, decreased, or altered. It is especially important to check with your doctor before combining Gris-PEG with the following: Blood-thinning drugs such as Coumadin, Barbiturates such as Phenobarbital, Oral Contraceptives.

General information:

f you have any questions about Gris-PEG Tablets, please talk with your doctor, pharmacist, or other health care provider.